Processing chemistry of brain, emptiness and consciousness, the scheme of its relations

Are the sensations of reality, including the “delivery of things as they are” created by the brain and its processing chemistry, or is it a direct connection? Is emptiness real and then what role does pure consciousness play in it? The world is material and exists independently of consciousness – no doubt here, that is a fundamental aspect of science as we used to know it. The human brain as the pinnacle of nature’s complexity reflects and processes the reality of matter through several levels – but nevertheless – continues to exist in its own juice

“One cannot contrast a thing as it is ‘in itself’ with what it appears to be from our limited, partial perspective; this visibility is more important than the thing in itself, for it determines how a given thing fits into the scheme of its relations with others.”